Cell Biology Lab Report - 1043 Words

BIO-2B06 Cell Biology Lab Report: Cell Adhesion Introduction As Akiyama suggests, cell-Cell interactions with solid substrates is important for their migration, proliferation, differentiation and their anchorage. Cells have the ability to attach or adhere, migrate and spread on a variety of glycoproteins located outside the cell, this occurs due to the presence of specific cell surface receptors, and example being integrins. 1 Integrins, as is again suggested by Akiyama, are non-covalent, heterodimeric glycoproteins that exist in 3 classes and are made up by an alpha and a beta subunit.1 External Structures are linked to the actin cytoskeleton of a cell by integrins. The part of the integrin, which is located in the cytoplasm binds to adaptor molecules that connect the acting filaments inside the cell, while the â€Å"external† part of the integrin, binds to other molecules or ECM’s on the surface of other cells. 2 For a cell to form a junction to another cell the external integrins must adhere to other molecules in other cells a nd this is achieved by assembling a large cytoskeletal apparatus around the molecules that facilitate the adhesion. There are several types of structures that result from cell adhesion, like a desmosome, adherens junction, tight junction, gap junction and hemidesmosome, all illustrated in Image 1 below. 3 In the present, cell-matrix interactions including cell adhesion and the important part that integrins play in it, is the focus ofShow MoreRelatedCell And Molecular Biology Lab Report Essay1826 Words   |  8 PagesCarijo Taro Cell and Molecular Biology Lab September 30, 2015 Cell Motility Lab Report Introduction: Cell movement involves both the interactions between signaling molecules and the structure of the cytoskeleton (Holmes et al., 2012). Tiny hair like structures referred to as cilia are located on the surface of eukaryotic cells. 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